Nucala

Nucala is a humanized monoclonal antibody that targets human Interleukin-5 (IL-5), it is indicated for add on maintenance treatment of patients 6 years and older with severe asthma with eosinophilic phenotype.

Inflammation is an important component of asthma development. It is mediated by multiple cell types which include eosinophils, a type of white blood cell that protects the body from parasites, allergens and foreign bacteria.

Eosinophilic inflammation can be characterized by high eosinophilic count via bloodwork. IL-5 is a major cytokine which is responsible for eosinophil development.

Nucala binds and targets IL-5 blocking. IL-5 binds to the alpha chain of the IL-5 receptor complex. This prevents IL-5 signaling, reducing the production and survival of eosinophils.

What is Nucala?

  • Severe asthma and with an eosinophilic phenotype

  • Chronic rhinosinusitis with nasal polyps (CRSwNP)

  • Eosinophilic granulomatosis with polyangiitis (EGPA)

  • Hypereosinophilic syndrome (HES)

What Does Nucala Treat?

  • Hypersensitivity reaction

  • Headache

  • Injection site reaction

  • Back pain

  • Fatigue

  • Joint pain

  • Click here for additional side effects

Possible Side Effects

Injection Duration

5-10 minutes

Injection Cycle

Every 4 weeks

  1. Remember to drink plenty of water so you are hydrated for your appointment.

  2. Your nurse will review your medical history, check your vitals, and discuss any questions and potential side effects of your infusion therapy.

  3. Your nurse will begin your infusion and monitor you closely during your treatment.

  4. You’ll continue to be monitored for 30 minutes post your infusion to ensure there are no reactions to the therapy.

IMPORTANT: Remember to let us know of any changes in your insurance prior to your visit to ensure that we are still an in-network provider for your infusion therapy.​

What to Expect During Your Infusion:

Why Patients Choose Flourish for Infusion Treatments

At Flourish, our mission is providing patients with expert medical care and a relaxing spa-like infusion experience. Data suggests that care at ambulatory infusion centers costs over 50% less than the same services offered at hospitals. We also increase affordability with co-pay assistance and additional financial aid programs to our patients. Our clinical model ensures a 3:1 patient to nurse ratio. Popular entertainment streaming options, high speed WiFi access, relaxing recliners, and delicious food and beverage selections pamper patients and provide them with an experience they can enjoy for hours.